Silica dioxide- vs nanofiber

Catalog	ACM60676860-11
CAS	60676-86-0
Structure
Synonyms	Nanofibrous inorganic powder structure
Molecular Weight	60.08
Molecular Formula	SiO2
Application	Inorganic nanofibers have unique properties (i.e. high surface area, high porosity, good breathability, large surface to volume ratio, and stability) their applications include anodes and cathodes in li-ion batteries. They can additionally act as a fuel cell separator, catalyst, catalyst support, photo catalyst, gas sensors, thermal insulators, metal or ceramic nano-composites, dehumidifiers, abrasives, thermal barrier coatings, and filtration.
Form	nanofiber
Packaging	5g/10g

Case Study

Superelastic Composite Aerogels Integrated with SiO2 Nanofibers Designed for Tissue Engineering Applications

Liu, Mingyue, et al. Advanced Healthcare Materials, 2022, 11(15), 2200499.

Bone defect repair benefits from scaffolds that match defect sites precisely and support both bone formation and blood vessel development. The research aimed to create superelastic composite aerogel scaffolds through the integration of silica nanofibers (SiO2) with poly(lactic acid)/gelatin (PLA/gel) nanofibers. Scaffold types emerged from a range of SiO2 content between 0% and 60 wt% marked as PLA/gel for 0%, PLA/gel/SiO2-L for 20%, PLA/gel/SiO2-M for 40%, and PLA/gel/SiO2-H for 60% SiO2. The PLA/gel/SiO2-M scaffold demonstrated outstanding elastic properties alongside strong mechanical strength.
The PLA/gel/SiO2-M scaffolds were found to release silicon ions which stimulated rat bone marrow mesenchymal stem cells to become osteoblasts while increasing alkaline phosphatase activity and bone-related gene expression. These silicon ions promote both human umbilical vein endothelial cell growth and vascular endothelial growth factor production which supports angiogenesis. The PLA/gel/SiO2-M scaffold shows great promise in bone regeneration according to calvarial defect model tests with rats because it supports bone growth and stimulates both osteogenesis and angiogenesis.

SiO2 Nanofiber Fillers for Dental Composite Reinforcement

Wang, Xiaoyan, et al. Materials Science and Engineering: C, 2016, 59, 464-470.

This study explored the impact of silica (SiO2) nanofibers on the characteristics of dental composites made from 2,2-bis-[4-(methacryloyloxypropoxy)-phenyl]-propane (Bis-GMA) and tri(ethylene glycol) dimethacrylate (TEGDMA). The mechanical properties of Bis-GMA/TEGDMA resins (50/50 w/w) with varying concentrations of SiO2 nanofibers were assessed, leading to the identification of optimal levels (5 or 10 wt.%) of nanofibers to be combined with SiO2 microparticles, which comprised 60 wt.% of the resin.
Effect of SiO2 nanofiber additives
• Unlike SiO2 nanoparticles, incorporating SiO2 nanofibers enhanced the overall functionality of Bis-GMA/TEGDMA composites, particularly in terms of abrasion resistance and reduced polymerization shrinkage.
• The use of one-dimensional SiO2 nanofibers with high aspect ratios facilitated the establishment of fibrous network structures, which were conceptualized as the "skeleton" of the composite resins. This structure not only reinforced the composite and minimized polymerization shrinkage but also improved wear resistance by protecting the fillers from erosion during abrasion.
• These findings suggest that Bis-GMA composite resins containing SiO2 nanofibers are a promising option for achieving durable restorations in clinical applications.