Chitosan-High DDA%-Medium Mol. Wt.

Catalog	ACM9012764-50
CAS	9012-76-4
Description	High DDA% – Medium Mol. Wt.
Molecular Weight	250-300 kDa
Molecular Formula	(C6H11NO4)n
Appearance	White to light yellow powder
Application	Biocompatible, antibacterial and environmentally friendly polyelectrolyte with a variety of applications including water treatment, chromatography, additives for cosmetics, textile treatment for antimicrobial activity, novel fibers for textiles, photographic papers, biodegradable films, biomedical devices, and microcapsule implants for controlled release in drug delivery.
Storage	<25°C, cool dry environment, well-sealed
Feature	Degree of Deacetylation (DDA) – 90.1%
Form	Powder
Moisture Content	0.062
Packaging	100g, 250g
Particle Size	100% pass 80 mesh
pH	8
Type	Source: Mushroom - Fungal, Non-Animal, Vegetal, Plant-Based Source

Case Study

Chitosan Fiber-Loaded Zero-Valent Iron Nanoparticles for Inorganic Arsenic Adsorption

Horzum N, et al. RSC advances, 2013, 3(21), 7828-7837.

Monodispersed nano-zero-valent iron (nZVI) (75-100 nm) particles were deposited on the surface of electrospun chitosan fibers (average fiber diameter 195 ± 50 nm) by liquid phase reduction. The prepared chitosan composite fiber was a great adsorbent material to remove inorganic arsenic (arsenite and arsenate ions) in concentrations from 0.01 to 5.00 mg L-1 and a wide range of pH.
Preparation of chitosan fiber-supported nZVI
· A 0.4 wt% chitosan solution in HFIP was transferred to a 20 mL plastic syringe with a needle to produce mat-like chitosan films by electrospinning. The main spinning parameters included: 10.5 kV potential, spinning solution flow rate maintained at 7.5 mL h-1, and tip-to-collector distance of 5 cm.
· The nZVI nanoparticles were reduced by in-situ reduction on chitosan fibers. Iron(III) chloride hexahydrate (1.35 g) was mixed in 25 mL of ethanol/water (4:1 v/v), and added 24 mg of chitosan fibres to the solution, stirring for 30 minutes. BH4-/Fe3+ molar ratios (1:1, 2:1, and 3:1) were applied to the Fe(III)-loaded fibers and exposed to sodium borohydride solutions. The Fe(III) concentration remained constant while the NaBH4 concentration was increased incrementally. Dropwise addition of NaBH4 solution to the fiber mat under stirring initiated the reduction of Fe(III) to Fe(0), evident by the formation of black iron particles.

Chitosan-Gelatin Microcapsules for Antibacterial Modification of Cotton Fabrics

Liu J, et al. Colloids and Surfaces B: Biointerfaces, 2013, 109, 103-108.

Patchouli oil-entrapped chitosan-gelatin microcapsules were prepared by complex coacervation, then crosslinked on to cotton fabric with 2D resin (dihydroxymethyl dihydroxyethylene urea, DMDHEU) as crosslinker to produce antibacterial modification. The antibacterial activity after 25 washes of the modified antibacterial fabric against Staphylococcus aureus and Escherichia coli is still about 65%, indicating the uses for antibacterial masks, antibacterial tablets and more.
Preparation of the chitosan-gelatin microcapsules
· There were solutions of chitosan (deacetylation degree 89%) and gelatin solution should prepared. The first solution, solution A, was prepared by dissolve 0.45 g of chitosan in 60 mL of 0.5% acetic acid for 0.75% chitosan solution. For solution B, 1.35 g of gelatin, 1.8 g patchouli oil and 1.25 g span-80 were added to 180 mL of distilled water and emulsified at 2500 r/min.
· Then solution B was added to a 500 mL three-neck flask, placed in a water bath at 50°C and stirring at 400 r/min, and then solution A slowly added to the emulsion. After that a 10% NaOH solution was added to raise the pH to 5.3 and it was stirred for 30 minutes.
· The reaction mixture was then iced to 5-10 °C in an ice bath and 2 mL of 25% glutaraldehyde added dropwise over 30 minutes. Finally, the flask was immersed in 40 °C water bath and the microcapsule suspension was obtained by stirring continuously for 2 hours.